
The last time Massachusetts elected a Republican to the U.S. Senate in a regular election was 1972. That streak won't be ending this year. The presumptive GOP nominee is John Deaton, the only Republican who filed to run. He got thrashed by Sen. Elizabeth Warren (D-MA) two years ago, losing by 20 points. This poll is a bit presumptive because Sen. Ed Markey (D-MA) hasn't won his primary yet, but since he is 30 points ahead of challenger Rep. Seth Moulton (D-MA), it's almost certain to be Markey vs. Deaton. (Z)
| State | Democrat | D % | Republican | R % | Start | End | Pollster |
| Massachusetts | Ed Markey* | 51% | John Deaton | 30% | Aug 05 | Aug 12 | U. of Massachusetts |